Heparin-bonded expanded polytetrafluoroethylene femoropopliteal bypass grafts outperform expanded polytetrafluoroethylene grafts without heparin in a long-term comparison
Samson et al. 20161
Sarasota Vascular Specialists in Sarasota, Florida, USA
Primary patency of GORE® PROPATEN® Vascular Graft
![N=87](/sites/default/files/styles/max_750x750/public/2019-06/samson-1.gif.webp?itok=YWTdAB0A)
![1 year 92%](/sites/default/files/styles/max_750x750/public/2019-06/samson-2.gif.webp?itok=qLC6DbHt)
![2 years 85%](/sites/default/files/styles/max_750x750/public/2019-06/samson-3.gif.webp?itok=_kXcelsT)
![3 years 85%](/sites/default/files/styles/max_750x750/public/2019-06/samson-4.gif.webp?itok=yAYyfp2i)
![4 years 85%](/sites/default/files/styles/max_750x750/public/2019-06/samson-5.gif.webp?itok=QZtqGZmp)
![5 years 85%](/sites/default/files/styles/max_750x750/public/2019-06/samson-6.gif.webp?itok=DJkawEia)
Patient characteristics*
Characteristic | N | % |
---|---|---|
Gangrene | 27 | 20% |
Ulceration | 39 | 30% |
Rest pain | 40 | 30% |
Claudication | 43 | 33% |
Runoff vessels | ||
0 | 2 | 2% |
1 | 44 | 37% |
2 | 49 | 41% |
3 | 24 | 20% |
Hypertension | 110 | 84% |
Diabetes | 59 | 45% |
Smoking | 42 | 32% |
Study details
- Retrospective, non-randomized, single-center review of prospectively collected data
- No adjunctive technique (patches or cuffs) were used
- Most grafts were 6 mm ring reinforced
- Clopidogrel usage had a significant benefit on overall primary patency
- Loss of patency was found to be related to younger age, absence of claudication, isolated popliteal artery, and lower post-operative ABI
- As early as 3 months, a significant difference in patency favoring GORE® PROPATEN® Vascular Graft was seen and was maintained at 5 years (74.5% vs 56.2%), and in both AK (85.2% vs 59.3%) and BK (59.6% vs 0.0%/undeterminable) locations
These data show that the [GORE® PROPATEN® Vascular Graft] offered significantly better long-term patency over the SePTFE graft, suggesting [GORE® PROPATEN® Vascular Graft] as the prosthetic graft of choice for bypasses to the femoropopliteal artery when autologous vein is unavailable or inappropriate. — RH Samson
[GORE® PROPATEN® Vascular Grafts] seem to be as effective as vein for AK femoropopliteal artery bypass. Because of the excellent results observed in this series, we now use the [GORE® PROPATEN® Vascular Graft] preferentially over great saphenous vein for AK bypass except in younger patients with available appropriate autologous conduit. — RH Samson
* GORE® PROPATEN® Vascular Graft group
1. Samson RH, Morales R, Showalter DP, Lepore MR, Nair DG. Heparin-bonded expanded polytetrafluoroethylene femoropopliteal bypass grafts outperform expanded polytetrafluoroethylene grafts without heparin in a long-term comparison. Journal of Vascular Surgery 2016;64(3):638-647.