Results from a multicenter registry of heparin-bonded expanded polytetrafluoroethylene graft for above-the-knee femoropopliteal bypass

Piffaretti et al. 20181

Department of Cardiovascular and Thoracic Surgery, Imelda Hospital, Bonheiden, Belgium

Primary patency of GORE® PROPATEN® Vascular Graft

N=360
1 year 82%
2 years 77.5%
3 years 74%
4 years 71%
5 years 64%

Patient characteristics

Characteristic N %
Rutherford classification  
3 200 55%
4 86 24%
5 68 18%
6 10 3%
Hypertension 294 81%
Diabetes 141 39%
History of smoking 216 59%

Study details

  • Retrospective, non-randomized, multi-center analysis

  • At the time of publication, the PROPATEN Italian registry had tracked 1,401 interventions performed for peripheral arterial obstructive disease using GORE® PROPATEN® Vascular Graft in a “real-world” setting

  • Estimated survival at 5 years was 75.3%

  • Estimated amputation-free survival at 5 years was 74%

  • Estimated assisted primary patency, secondary patency, and limb salvage at 5 years were 65%, 74.5%, and 95%, respectively

  • Postoperative medical treatment with warfarin alone was found to be an independent risk factor for loss of primary patency compared to dual antiplatelet therapy

[Above-the-knee femoropopliteal bypass] with the use of HB-ePTFE remains an effective option, with low rate of perioperative complications and satisfactory long-term results. — G. Piffaretti

…in our opinion, [Above-the-knee femoropopliteal bypass] is a valid and viable first-line alternative to endovascular surgery in long or complex lesions of the SFA. — G. Piffaretti

1. Piffaretti G, Dorigo W, Castelli P, Pratesi C, Pulli R. PROPATEN Italian Registry Group. Results from a multicenter registry of heparinbonded expanded polytetrafluoroethylene graft for above-the-knee femoropopliteal bypass. Journal of Vascular Surgery 2018;67(5):1463-1471.e1.

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