Heparin-bonded expanded polytetrafluoroethylene graft for infragenicular bypass: five-year results

Lösel-Sadée and C. Alefelder, 20091

Department of Vascular Surgery, Sana Kliniken Dusseldorf, Dusseldorf, Germany

Primary patency of GORE® PROPATEN® Vascular Graft

N=30
1 year 77%
2 years 71%
3 years 71%
4 years 71%
5 years 71%
N=45
1 year 64%
2 years 57%
3 years 50%
4 years 50%
5 years 50%

Patient characteristics

Characteristic N %
Rutherford classification  
3 6 8%
4 43 57%
5 25 33%
6 1 < 1%
Vessel runoff  
1 41 55%
2 18 24%
3 16 21%
Hypertension 72 96%
Diabetes 37 49%
Renal insufficiency 23 31%
BK fem-pop* 30 40%
Infrapopliteal 45 60%
TP trunk 12 27%
Anterior tibial 14 31%
Posterior tibial 9 2%
Peroneal 9 2%
Dorsalis pedis 1 < 1%

Study details

  • Retrospective, non-randomized, single-center study
  • Vein cuffs were created at the distal anastomosis in five patients; no patches were used
  • The 3- and 4-year secondary patency rates for below-knee fem-pop and infrapopliteal bypasses were 83% and 72%, respectively
  • The 5-year limb salvage rate was 84%

The primary patency results are especially encouraging in light of the fact that the patients were seriously ill, as indicated by the high rates of Rutherford category 4 to 6 disease, renal insufficiency, and previous treatment for PAD and the low rate of multiple-vessel runoff in the series. — Lösel-Sadée

*Distal of the knee articulation

1. Lösel-Sadée H, Alefelder C.  Heparin-bonded expanded polytetrafluoroethylene graft for infragenicular bypass: five-year results.  Journal of Cardiovascular Surgery 2009;50(3):339-343.

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